Aunque se trata de una serie corta de pacientes, coincide con otros estudios de inhibidores del RFCE en que las manifestaciones ms frecuentes son la erupcin acneiforme, la paroniquia y la xerosis
Vitamin C: Necessary for the formation of connective tissues and maintenance of their function, necessary for iron absorption, necessary for protecting cells from harmful oxygen by acting as an antioxidant Calcium: Supports bone and tooth formation, maintenance of nerve and muscle function, and normal blood coagulation, and helps reduce the risk of osteoporosis
*Gradually reduces dark spots and dark areas
Tyr is synthesized via two alternative routes mediated by a TyrA family enzyme, prephenate, or arogenate dehydrogenase (PDH/TyrA p or ADH/TyrA a ), typically found in microbes and plants, respectively