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*Correspondence: Miriam Kolko, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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It remains unclear, however, whether such effects mitigate hypoxia risk and ultimately fibrosis and nephron loss as described below