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This variation is associated with increased antagonistic activity of agouti signaling protein, which can more strongly compete with melanocortin signals such as -MSH and its analogs like Melanotan-1 at the MC1R receptor

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Compromised healing environments : Perhaps most intriguingly (and this is what catches my attention as a surgeon), BPC-157 appeared to promote healing even in situations where recovery was impaired, such as tissues affected by corticosteroid use or areas with very poor blood supply

10.1126/science.1166304 20 DukhinovaM.KokinosE.KuchurP.KomissarovA.ShtroA