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In the most immediate period after injury induction (skin defect) (i.e., 2, 5, and 10 min), BPC 157 increases Akt1, Braf, Egfr, Egr1, Grb2, Hdac7, Kras, Mapk1, Mapk3, Mapk14, Nos3, Pik3cd, Plcg1, Prkcg, Ptk2, Pxn, Src, Srf, and Vegfa gene expression in rats excision wounds in the skin
That is a real risk arguably a greater one than the theoretical risks the FDA cited when it enacted the 2023 restrictions
Research suggests this dual action creates cellular conditions that favor energy expenditure over energy storage, giving researchers a tool to study metabolic switching mechanisms