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By subsequently inhibiting carnitine biosynthesis, fatty acid transport is reduced and the accumulation of cytotoxic intermediate products of fatty acid beta-oxidation in ischemic tissues to produce energy is prevented, therefore blocking this oxygen-consuming process

Elrick H, Stimmler L, Hlad C, Arai Y: Plasma insulin response to oral and intravenous glucose administration

Quick Answer: GLP-1 receptor agonist-related fatigue likely results from multiple indirect mechanisms including substantial caloric restriction, gastrointestinal side effects causing dehydration and nutritional deficits, and metabolic adaptation during weight loss, rather than a single direct pharmacological effect

Monitoring any changes in menstrual patterns and discussing them with a healthcare professional is essential