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The study was published in Frontiers in Nutrition in September 2023
K., & Pereira, K
N-acetylcysteine was documented to attenuate alcohol-induced oxidative stress in the mouse liver [14], and methionine supplementation has been shown to exhibit antioxidant activity by upregulating the expression of antioxidant enzymes in mice [15]
Nonetheless, our study demonstrates that a persistent imbalance between oxidative stress toxicity and reduced ANTIOX is a key component of Long COVID and that increased aldehyde, neutrophil-associated MPO, protein carbonyl, and NO production are the major neurotoxic pathways, which, when combined with decreased ANTIOX, may have a variety of detrimental effects as reviewed before [81]
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