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That is, the crystallographic two-fold axis relating the monomers within the dimer is perpendicular to the membrane, the N-terminal myristoylation motif serves as two-pronged membrane anchors, and the CTD may also be involved in membrane association, consistent with a model calculated using PPM server 30 (Supplementary Fig

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Prevents Type 2 Diabetes Progression By improving insulin sensitivity and beta-cell function Supports Cardiovascular Health Reduces blood pressure, LDL cholesterol, and inflammation Lowers Risk of Fatty Liver Disease (NAFLD/NASH) Helps reduce liver fat accumulation Improves PCOS Symptoms Regulates ovulation, insulin resistance, and weight in women with PCOS May Benefit Neuroprotection Early studies suggest a role in reducing neuroinflammation and cognitive decline Contraindications These GLP-1s are generally well-tolerated, but some patients should not take them