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In a large analysis using the TriNetX database including 15,176 propensity-matched pairs of patients with type 2 diabetes and MASLD, initiation of GLP-1 receptor agonists was associated with a significantly lower risk of composite MALOs compared to sodium-glucose cotransporter 2 inhibitors (adjusted hazard ratio [aHR] 0.84) [131]
Not everyone loses weight on a GLP-1 medication, and sadly, most patients do not have access to them in the long term, from a combination of insurance restrictions and side effects, she said
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