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MOTS-c is also contraindicated for people who take AMPK-activating medicines, such as metformin , thiazolidinediones , and aspirin , as well as anyone with an active cancer diagnosis and people who are pregnant or breastfeeding

Phenylpropanolamine is a chemical analogue of the endogenous sympathomimetic amines

Long-acting agents, on the other hand, provide continuous receptor activation due to structural modifications that slow their absorption, reduce the rate of renal clearance or extend their half-lives [52, 53]

It is a novel triple agonist that simultaneously targets the glucagon-like peptide-1 (GLP-1) , glucose-dependent insulinotropic polypeptide (GIP) , and glucagon receptors