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Aging Cell 23 , e14138 (2024)

APOE targeting strategy in Alzheimer's disease: lessons learned from protective variants

Drawing parallels to cardiovascular medicine, where combinations of antithrombotics, antihypertensives, and lipid-lowering drugs have substantially improved patient outcomes, they highlight the possibility that neuroinflammation inhibitors could both mitigate Alzheimers risks and enhance the benefits of antibody-based treatments