Cellular-Response Research Research involving GHK-Cu has explored its interaction with: Cellular-repair and regenerative signaling pathways Oxidative-stress and antioxidant-defense mechanisms Tissue-remodeling and extracellular-matrix pathways Cellular-response and physiological-maintenance signaling Because GHK-Cu interacts with regenerative and growth-related pathways, some research settings involving active cancer-, tumor-, or abnormal proliferative research models may warrant additional monitoring and individualized evaluation
Proteins from this class are not homogeneously distributed in the cell and are rather localized to several subcellular compartments, such as the nucleus and its membrane, cytoskeleton, centrosome, and cytoplasm (Zhao et al, 2021b)
Liu H, Zhao Z, Zhang L et al (2019) Discovery of low-molecular weight anti-PD-L1 peptides for cancer immunotherapy
However, future study needed especially on stability since it still remains a significant barrier