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However, this study has certain limitations that warrant further investigation

AIN457 An anti-IL17 antibody, shows good safety and induces clinical responses in patients with active rheumatoid arthritis (RA) despite methotrexate therapy in a randomized, double-blind, proof of concept study

These features make KLOW of interest in research on injury recovery, skin health, inflammation control, and overall tissue repair, though it is still experimental and not approved for medical use

The closest human data is from CB4211, an analog that completed a Phase 1a/1b safety trial (NCT03998514) with well-tolerated SubQ dosing and favorable liver-enzyme and glucose trends