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The cardiovascular outcomes data expected from dual GLP-1/amylin therapies offers a great opportunity for differentiation of the product in the market on a basis of greater cardiovascular risk reduction than the current GLP1 monotherapy standards

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The response of an increase in ARNA to intrapelvic injection of GLP-1 was enhanced in HF

These include uncontrolled diabetes, active infections, a history of HIV/AIDS or Hepatitis B/C (permanent disqualification), certain severe heart or lung diseases, certain autoimmune disorders, and a history of specific types of organ or tissue transplants