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However, they emphasize that this is not common and usually not severe

Such inflammation-associated oral mucosal melanin hyperpigmentation occurs most commonly in darker skinned persons and usually manifests as single or multiple brown-black patches, which may persist for a long time after the resolution of the inflammatory process [6, 11, 37]

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This triple activation is what makes it so effective for fat loss , with Phase 2 data showing up to 24% body weight reduction