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"Metabolic studies of a synthetic C-terminal fragment of human growth hormone (AOD9604)." Journal of Endocrinology 166.3 (2000): 75-85

Standard rapid-release formulas, even if absorbed, create a brief spike in blood levels followed by a rapid crash, whereas sustained-release formulations maintain a therapeutic window that provides round-the-clock cellular protection

doi: 10.3389/fendo.2019.00508 Received 12 May 2019 Accepted 12 July 2019 Published 13 August 2019 Volume 10 - 2019 Edited by Giuseppe Biagini, University of Modena and Reggio Emilia, Italy Reviewed by Cara Jean Westmark, University of Wisconsin-Madison, United States

Different patients'immune systems may respond differently to nanomaterialssome may exhibit heightened immune activation, recognizing nanomaterials as foreign substances and triggering strong immune rejection, leading to treatment failure or severe adverse reactions