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A few weeks ago, something happened quietly that could send shockwaves through the entire obesity drug market.

Weight-loss plateaus typically last 412 weeks and are not a sign of treatment failure

Reflecting a growing acceptance of obesity as a legitimate medical condition, at least in the United State, a 2024 employer health benefits survey found that 61% of respondents support expanding Medicare (federal health insurance program primarily for individuals aged 65 and older) coverage beyond treatment for T2DM to include GLP-1 therapies for weight management in overweight individuals (Kaiser Family, F, 2024)

Using standard behavioral tests, the researchers showed that liraglutide retained its antidepressant activity even in mice with GLP-1 receptors knocked out