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Journal of the Neurological Sciences, 347, 34-38

Vit-B12 is also an essential nutrient for skeletomusculargutbrain axis to maintain skeletal muscle, neuro-cognitive functions, and modulate gut microbiota 550,551

Both amounts remain within established safety thresholds for most healthy adults.51 52 Still, its worth keeping in mind especially for people who already supplement folate or vitamin D separately that combination products offer less flexibility when adjusting servings