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Description

While PT-141 does not directly act on dopamine receptors, melanocortin receptor activation in the hypothalamus appears to influence dopaminergic neurotransmission

Bjrnheden T, Levin M, Evaldsson M, Wiklund O

It was developed at the University of Arizona in the 1980s by the Hadley and Dorr teams as a tool for studying skin pigmentation and melanocortinergic signaling