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High soil pH, high manganese or high iron levels can reduce cobalt transfer from the soil to the plant

Chronic conditions impacting absorption include atrophic gastritis or pernicious anaemia, where there is a lack of intrinsic factor, a protein essential for the uptake of B12 in the digestive tract

Oral supplements require higher doses because only approximately 1% is absorbed passively when intrinsic factor is impaired, making injections the most reliable method for pernicious anaemia and malabsorption conditions

If you experience muscle cramps, weakness, or an irregular heartbeat, consult your healthcare professional