In diabetes-related gastrointestinal complications Its metabolic regulatory properties could assist in improving abnormal gastrointestinal motility and dyspepsia, reducing symptoms such as nausea, vomiting, and constipation
Hu X, Hu C, Zhang C, Zhang M, Long S, Cao Z
doi:10.1056/NEJMoa1607141 298
Melanin macroglobules (large pigment particles resulting from fusion of autophagosomes containing varying numbers of melanosomes) may be found in CALMs, but they are not specific for neurofibromatosis, as they are occasionally found in isolated CALMs (without any underlying disease) and occur in several other conditions such as simple lentigines, Becker melanosis, congenital melanocytic nevi, and sometimes even normal skin