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PMID 10369661

Several factors can deplete hepatic glutathione stores: Chronic alcohol consumption that overwhelms detoxification pathways Acetaminophen overdose or prolonged use of hepatotoxic medications Metabolic dysfunction associated with obesity and insulin resistance Viral hepatitis and chronic inflammatory conditions Age-related decline in antioxidant enzyme production Understanding these mechanisms helps explain why both glutathione and NAC have become subjects of intense clinical research for liver support and repair

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See a medical professional if you experience any side effects