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This has prompted researchers to explore ways to inhibit glutathione synthesis in cancer cells as a strategy to enhance chemotherapy effectiveness

4.5 Mitophagy and diabetes complications Diabetes mellitus is a type of metabolic disease caused by abnormal lipid metabolism or insulin dysfunction, and persistent chronic elevation of blood glucose and long-term metabolic disorders can damage tissues and organs throughout the body, leading to complications such as diabetic kidney disease (DKD), diabetic cardiomyopathy (DCM), and diabetic muscle atrophy (Wen et al., 2023)

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia