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Historically, the clinical use of oral glutathione has been heavily debated

In extreme cases, it can be life-threatening, leading to seizures, loss of consciousness, disorientation, and blurred vision

Successful efferocytosis not only prevents the secondary necrosis of apoptotic cells and the subsequent release of intracellular contents that can incite inflammation, but it also prompts phagocytes to secrete anti-inflammatory factors, such as IL-10 and TGF-, along with growth factors that support tissue repair

The drug was approved by Health Canada in November 2021, however shortages delayed its release until now