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[1] Understanding this pharmacological impact on digestion helps explain why certain dietary modifications can significantly improve tolerability

CormeraisYMassardPAVuceticMGiulianoSTambuttEDurivaultJet al

Our structure identified an unpredicted non-peptide agonist-binding pocket in which reorganization of extracellular loop 3 and transmembrane helices 6 and 7 manifests independently of direct ligand interaction within the deep transmembrane domain pocket