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In a 2018 double-blind trial of 100 depressed patients, 1,000 mcg/day adjunct therapy lifted mood scores by 35% after 3 months, outperforming antidepressants alone

4 However, direct evidence that EGT enhances mitochondrial respiration in humans is currently lacking, and available animal data primarily indicate cytoprotection under exercise-induced stress rather than a confirmed primary role as an energy production modulator

This is crucial for athletes who rely on their joints for optimal movement and performance in their respective sports

Neilson R, Caul S, Fraser FC, King D, Mitchell SM, Roberts DM, Giles ME