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Cells were incubated with CellROX TM green reagent (ThermoFisher Scientific) for 30-min prior to the addition of conditioned media

Tirzepatide is not recommended for those with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome.

Fatima Cody Stanford, an obesity specialist at Massachusetts General Hospital , said, "My assumption would be that they're making an agent that's close," but that "I can't chance anything with my patients