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There are several possible explanations, says Laffin

For most working professionals, Friday evening or Saturday morning works well because the peak side effect window falls on the weekend

A dedicated Phase 3 trial evaluating retatrutide specifically for metabolic dysfunction-associated steatotic liver disease is currently underway

Enrolment of female participants is capped at approximately 70% to ensure sufficient male representation, given that participants typically seeking enrolment in obesity trials have been disproportionately female