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As estrogen levels fluctuate and then decline, the body tends to move away from a more pear-shaped pattern (hips and thighs) toward increased abdominal and visceral fat (fat around the organs)

Perrin F, Pernier J, Bertrand O, Giard MH, Echallier JF (1987)

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Mindful of studies implying an anxiogenic role for the LS (3739), we explored whether the altered consumption could be attributed to changes in anxiety levels and found that LS GLP-1R :TeNT mice exhibited similar anxiety levels and locomotor activity in an open-field test compared with control mice (Supplemental Figure 7, N and O)