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Dogs have the same thymosin beta-4 system, and what works for equine ligament injuries tends to show up in canine protocols too

33 NACs clinical benefits may stem from multiple mechanisms besides GSH replenishment, including ( i ) indirect antioxidant effects, ( ii ) provision of hydrogen sulfide (H 2 S) and sulfane sulfur with anti-inflammatory properties, 14,19,37,38 or ( iii ) an impact on NO regulation

Furthermore, elevated NTBI levels stimulate monocyte chemoattractant protein (MCP-1) expression in ECs and vascular smooth muscle cells (VSMCs), thereby attracting monocytes/macrophages and accelerating foam cell formation and plaque evolution [181, 182]