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Once reconstituted, the liquid solution must be continuously refrigerated at 4C to prevent degradation

PLoS One 7 , e32637 (2012)

Since IL-17 receptor A (IL-17RA) has been shown to mediate communication from the meninges to the cortex 47 , we next examined whether the beneficial effect of peripherally targeting CD38 could be mediated in part through modulation of cortical IL-17RA and IL-1 signaling, which we observed to drive T H 17 pathogenicity