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, : Rising global prevalence of obesity and diabetes Strong clinical success of GLP-1 receptor agonists Growing investments from leading pharmaceutical companies Expansion into cardiovascular and metabolic health indications Increasing demand for effective long-term weight management solutions Breakthrough therapies from global innovators are reshaping how metabolic diseases are managed

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A cardiovascular risk assessment tool widely used in primary prevention, especially in the primary care setting, is the Pol-SCORE scale (Figure 2) [48], a modification of the SCORE ( systemic coronary risk evaluation ) scale developed by the European Society of Cardiology (ESC) experts