In Journal of Clinical Investigation (Vol
Compared with controls, GLP-1 agonist therapy reduced HbA1c by -0.30% with a larger effect in children with (pre-)diabetes (-0.72%) than in children with obesity (-0.08%)
Fetal anomalies targeted with prenatal pharmacotherapy are a heterogeneous group of structural, endocrine, and metabolic conditions, including brain and spine anomaly, hyaline membrane disease prevention, congenital cystic adenomatoid malformation (CCAM), congenital adrenal hyperplasia, congenital heart block, fetal tachyar- rhythmia, inborn errors of metabolism, fetal thyroid disorders, and polyhydramnios
Scientific investigations also examine BPC-157 in relation to intracellular signaling pathways involving nitric oxide synthase (NOS) , FAK/paxillin signaling , ERK/MAPK pathways , PI3K/Akt signaling , transcriptional regulation, cytoskeletal organization, and peptide-mediated molecular communication