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Results observed in one study or experimental model should not be expected in every research setting

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382 Impaired astrocytic iron homoeostasis triggers secondary neuronal iron toxicity, which together with loss of astrocytic homoeostatic support, triggers neuronal death

In some instances, controlled release is delayed release, extended release, sustained release and/or pulsatile release (e.g., a combination of extended release and immediate release) or a combination thereof