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Hormonal fluctuations, particularly in females, can affect ligament laxity and susceptibility to injury, as variations in estrogen levels have been linked to changes in the mechanical properties of the ACL

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The effect size was robust (Hedges g = 0.98), indicating a pronounced depletion in antioxidant capacity in this region

Understanding the impact of renal or hepatic impairment on the pharmacokinetic properties of cagrilintide is crucial for managing overweight and obesity in individuals with these conditions, particularly as chronic kidney disease and liver disease including metabolic dysfunction-associated steatotic liver disease are common comorbidities of obesity