In support of this, in the wall lizard cells, treatment with phosphodiesterase IBMX, which increases cAMP levels, resulted in a greater reduction in phagocytosis when combined with dopamine
Dopamine may induce these effects via regulation of the immune response in circulation (Beck et al., 2004), as dopamine can suppress inflammatory cytokines (IL-6, IL-8, and TNF- ) and increase production of IL-10, although, as previously noted, these effects are complex and vary with cell type, dopamine concentration, dopamine receptor ratio, and species
It improves angiogenesis ( new blood vessel formation) which is crucial because tendons are notoriously poorly vascularized
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