Common side effects include: Injection site reactions mild pain, redness, swelling, or bruising at the injection site, typically resolving within a few days Headache usually transient and manageable with standard analgesia Nausea or dizziness particularly in the initial treatment phase Skin reactions including itching, mild rash, or acneiform eruptions Temporary urine discolouration red or orange urine is harmless and expected Diarrhoea or flushing usually mild and self-limiting In patients with severe megaloblastic anaemia, low potassium levels (hypokalaemia) may occur during initial intensive treatment, but this is uncommon in routine maintenance therapy
Two separate injection windows, two separate syringes
They help strengthen the skin's natural barrier function, aiding the soothe irritated skin to promote overall skin condition
While APEX2 and HRP both showed BP labeling on the cell surface and in the ER lumen, LaccID was exclusively active on the cell surface, with no labeling detected from ER-targeted LaccID (Fig