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IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns

A personal or family history of thyroid cancer: Doctors usually will not prescribe Ozempic to people with a personal or family history of medullary thyroid cancer (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)

9 The CHMP also noted methodological concerns because the data showed a study dropout rate of approximately 40% and a lost to follow-up rate of more than 10%

The collaboration includes our most advanced preclinical metabolic program focused on developing an oral small molecule agonist to the GIP receptor