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Mental health concerns (depression or thoughts of suicide): Pay close attention to any new or worsening mental health symptoms, such as changes in mood, behaviours, thoughts, or feelings
This meta-analysis indicates that GLP-1 receptor agonists are safe and effective in modestly reducing weight, BMI, glycated hemoglobin A1c, and systolic blood pressure in children and adolescents with obesity in a clinical setting, albeit with increased rates of nausea [17]