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A 2025 study published in Biogerontology provided independent confirmation of these findings, demonstrating dose-dependent telomere length extension in normal human cells through upregulation of hTERT (human telomerase reverse transcriptase) mRNA expression

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Participants were randomly assigned, 1:1:1, to once-weekly combination cagrilintide and semaglutide 2.4 mg, once-weekly semaglutide 2.4 mg plus placebo or once-weekly cagrilintide 2.4 mg plus placebo