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The lower RMSF values for residues 200 to 400 in the Arbutin_d mode are hypothesized to be due to the hydroxyphenyl group of Arbutin_d facing the L3 region, where R289 tends to interact with the hydroxyphenyl group of Arbutin, stabilizing this region

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10.3390/ijms20112818 452 VaresiA.DeumerU.-S.AnanthS.RicevutiG

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