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Larson, C

Insufficient intake of magnesium, loss of magnesium through the digestive system and kidneys, and redistribution of magnesium from the extracellular space to the intracellular space are the main causes of magnesium deficiency (182)

A decrease in activity compared to the one of the free enzyme is due to the following reasons: (1) use of organic solvent for the immobilization procedure, which deactivates some parts of enzyme