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In a series of recent studies, we found that mitochondrial function in white adipocytes is essential to the synthesis of adiponectin, which is the most abundant adipokine synthesized from adipocytes, with many favorable effects on metabolism, including improvement of insulin sensitivity and reduction of atherosclerotic processes and systemic inflammation

These drugs are not approved by the FDA but patients may require them due to allergies or intolerances to certain approved medications

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This can cause those medications to be ineffective