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doi: 10.36349/easjacc.2020.v02i03.001 17 BanjacA.PerisicT.SatoH.SeilerA.BannaiS.WeissN.et al

Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system to preserve compound integrity throughout the supply chain

Before starting treatment, it is imperative to exclude that the edema is of systemic origin, such as in cases of heart, kidney, or liver failure, where the efficacy of vasoprotectants is not documented [EMA]