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Reductions in alcohol and substance use GLP-1 medications were associated with decreased alcohol consumption and reduced substance use in several studies from this 2024 review

Combining berberine and Saxenda may intensify gastrointestinal side effects including nausea, vomiting, and diarrhoea, potentially affecting treatment tolerability

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Toxicol in Vitro 25(8):17121720 Rudin CM, Yang Z, Schumaker LM, Vanderweele DJ, Newkirk K, Egorin MJ, Zuhowski EG, Cullen KJ (2003) Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance