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Moreover, decreased HR and cardiac contractility, increased thickness of the left ventricular wall and left ventricular developed pressure (LVDP) were also seen in GLP-1 -/- mice (109, 110)

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For adults over 50, this is particularly relevant because they have less margin before reaching thresholds associated with frailty

The evaluation of behavioral parameters such as seizure intensity and latency to the crisis can provide insights into the efficacy of these substances