When a destructive free radical threatens a cell, reduced glutathione directly donates a reducing equivalent (an electron or hydrogen atom) to neutralize the threat
Van Haren R, Rajaram R, Correa A, Sepesi B, d R, Hofstetter W, Roth J, Swisher SG , Walsh G, Vaporciyan A, Mehran R, Antonoff M
Concluding remarks The levels and compartmentalization of NAD + dictate energy state that impinges on normal physiological and biological responses, as indicated by the regulatory role of NAD + in proper redox homeostasis, genomic stability, gene expression, circadian clock, inflammation, metabolism, cellular bioenergetics, mitochondrial homeostasis and adaptive stress responses
A la difference des molecules hypnotiques classiques (benzodiazepines, Z-drugs, GHB), le DSIP n'agit ni par facilitation GABAergique directe, ni par sedation globale : les donnees animales suggerent une action fine de type "desynchronisation/resynchronisation" des cycles veille-sommeil, ce qui le differencie radicalement des hypnotiques anesthesiants
