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Side Effects and Safety Profile Common Side Effects Gastrointestinal effects are the most frequently reported adverse events in clinical trials: Nausea (reported by 1233% of participants depending on dose) Diarrhea (1223%) Constipation (611%) Vomiting (59%) Decreased appetite (considered both a therapeutic effect and side effect) Abdominal pain (58%) Dyspepsia/heartburn (58%) These effects are most common during dose escalation and typically improve within 24 weeks at each new dose level

Yes, you can discuss with your healthcare provider the possibility of switching to a branded version of semaglutide, which may offer more reliable dosing and safety standards

Inform patients to resume their regular once-weekly dosing schedule [see Dosage and Administration (2.4)]

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