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Native GLP-1 has been infused by the subcutaneous route (4.8 pmol/kg/min) using a portable insulin pump in a non-randomized study of subjects with type 2 diabetes over the age of 40 (mean age 55) with mean initial HbA1c of about 9%, and mean fasting glucose ~14 mM

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Raccah D, Huet D, Dib A et al (2017) Review of basal-plus insulin regimen options for simpler insulin intensification in people with type 2 diabetes mellitus