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The beta cell senses an elevated level of glucose in the plasma by glucokinase

Studies have shown that patients who receive Semaglutide GLP-1 injections experience significant weight loss compared to those who receive a placebo

Currently available GLP-1 receptor agonists have variable effects on fasting and postprandial blood glucose levels: short-acting GLP-1 receptor agonists have a greater effect on postprandial glucose and long-acting agents have a greater relative effect on fasting glucose ( Table 5 )

For many people, this represents an exciting alternative to weekly injections, offering the same active ingredient as the Wegovy pen in a simple daily tablet