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Kaplowitz, N., Aw, T

Retrieved from HydraMed

Ex vivo studies using dissected hair follicle organ cultures allow researchers to observe the effects of GHK-Cu on the hair cycle itself, particularly its potential to prolong the anagen (growth) phase

GHK-Cu influences follicle cycling through multiple mechanisms including stimulation of VEGF and hepatocyte growth factor (HGF) secretion from hair follicle cells, with research demonstrating that advanced delivery formulations achieve ~3-fold enhancement of GHK-Cu penetration while retaining biological function and stimulating dermal papilla cells at the base of follicles